Labels:text | screenshot | black | black and white | font OCR: ytochrome Metyrapone acts by interfering with the oxylation. P450 system and mainly affects 11 f-hyd duction of This causes a relative increase in the pro ycortisol, the immediate precursor steroid, 11-dec mthesis. with a concomitant decrease in cortisol These actions have been exploited in th al function development of a test of pituitary-adren which has been used clinically. See also: erapy . Cushing's Syndrome - Metyrapone T est · Differential Diagnosis - Metyrapone